Top 20 Skincare Best Sellers on TikTok Shop United States — April 2026

TL;DR

April puts an exclamation mark on medicube's lock over TikTok Shop US skincare. medicube US Store's PDRN Pink Collagen Multi Balm alone pulled $6.2M for the month — up +237% MoM, more than the next two SKUs combined. medicube takes 5 of the top 10, Dr.Melaxin another 4, leaving JiYuSkin as the only brand outside that duo in the top 10. Category-wide growth is a modest +4%, so this is concentration not breakout — medicube is reshaping its own share, not riding a category wave. The non-medicube/Dr.Melaxin signal worth tracking: JiYuSkin's $43 anti-aging serum is the only outsider, and it posted -24% MoM — suggesting tier-2 K-beauty is being squeezed by the medicube juggernaut.